T-448 free base is a selective, orally active, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1), targeting H3K4 demethylation with an IC50 of 22 nM. This compound promotes H3K4 methylation in primary cultured rat neurons, making it a valuable tool for investigating epigenetic regulation in neurobiology and related research applications.
T-448 free base is a selective, orally active, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1), targeting H3K4 demethylation with an IC50 of 22 nM. This compound promotes H3K4 methylation in primary cultured rat neurons, making it a valuable tool for investigating epigenetic regulation in neurobiology and related research applications.
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