τ-Fluvalinate is an insecticide primarily targeting the nervous system of pests. It selectively binds to the open state of voltage-dependent sodium channels, specifically Varroa destructor (VdNaV1) and Apis mellifera (AmNaV1), exhibiting EC50 values of 160 nM and 60 nM, respectively. Its higher affinity for AmNaV1 results in sublethal toxicity to honeybees, making τ-Fluvalinate a valuable tool for investigating Varroa destructor infestations in honeybee colonies and studying the impacts of insecticides on non-target species.
τ-Fluvalinate is an insecticide primarily targeting the nervous system of pests. It selectively binds to the open state of voltage-dependent sodium channels, specifically Varroa destructor (VdNaV1) and Apis mellifera (AmNaV1), exhibiting EC50 values of 160 nM and 60 nM, respectively. Its higher affinity for AmNaV1 results in sublethal toxicity to honeybees, making τ-Fluvalinate a valuable tool for investigating Varroa destructor infestations in honeybee colonies and studying the impacts of insecticides on non-target species.
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