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TAP311

Catalog No.: A69632
CETP Inhibitor
TAP311 is a selective inhibitor of cholesteryl ester transfer protein (CETP), exhibiting an IC50 of 62 nM. By blocking CETP activity, TAP311 effectively regulates lipid metabolism and enhances high-density lipoprotein (HDL) levels. This compound is valuable for research focused on cardiovascular disease, specifically in studies investigating the role of CETP in lipid regulation and atherosclerosis.
TAP311 1149362-88-8 CETP Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTAP311 is a selective inhibitor of cholesteryl ester transfer protein (CETP), exhibiting an IC50 of 62 nM. By blocking CETP activity, TAP311 effectively regulates lipid metabolism and enhances high-density lipoprotein (HDL) levels. This compound is valuable for research focused on cardiovascular disease, specifically in studies investigating the role of CETP in lipid regulation and atherosclerosis.
Product Information
Catalog NumA69632
FormulaC34H40F6N6O4
Molecular Weight710.71
CAS Number1149362-88-8
SMILESFC(F)(F)C1=CC(CN([C@@H]2C[C@H](CC)N(C(O[C@@H]3CC[C@@H](C(O)=O)CC3)=O)[C@H](CC)C2)C4=NC=C(C5=CN(C)N=C5)C=N4)=CC(C(F)(F)F)=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    V2

Metabolism > CETP