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Tarloxotinib bromide

Catalog No.: A20849

EGFR/HER2 inhibitor

Tarloxotinib bromide

Tarloxotinib bromide Chemical Structure

CAS NO. 1636180-98-7

Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor.

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Biological Activity

Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.67 mL 73.34 mL 146.68 mL
0.5 mM 2.93 mL 14.67 mL 29.34 mL
1 mM 1.47 mL 7.33 mL 14.67 mL
5 mM 0.29 mL 1.47 mL 2.93 mL

*The above data is based on the productmolecular weight 681.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20849
Actions Inhibitor
CAS No. 1636180-98-7
Formula C24H24Br2ClN9O3
M. Wt 681.77
Purity >98%
Synonyms TH-4000, TH4000, TH 4000
SMILES BrC1=C(Cl)C=CC(NC2=NC=NC3=C2C=C(NC(/C=C/C[N+](C)(C)CC4=C([N+]([O-])=O)N=CN4C)=O)N=C3)=C1.[Br-]

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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