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Biological Activity
Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.67 mL | 73.34 mL | 146.68 mL |
| 0.5 mM | 2.93 mL | 14.67 mL | 29.34 mL |
| 1 mM | 1.47 mL | 7.33 mL | 14.67 mL |
| 5 mM | 0.29 mL | 1.47 mL | 2.93 mL |
*The above data is based on the productmolecular weight 681.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20849 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1636180-98-7 |
| Formula | C24H24Br2ClN9O3 |
| M. Wt | 681.77 |
| Purity | >98% |
| Synonyms | TH-4000, TH4000, TH 4000 |
| SMILES | BrC1=C(Cl)C=CC(NC2=NC=NC3=C2C=C(NC(/C=C/C[N+](C)(C)CC4=C([N+]([O-])=O)N=CN4C)=O)N=C3)=C1.[Br-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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