Tasquinimod-d3 is a deuterated form of Tasquinimod, an oral antiangiogenic agent targeting castration-resistant prostate cancer. This compound selectively binds to the regulatory Zn2+ binding domain of HDAC4 with a Kd of 10-30 nM, thereby influencing histone deacetylation processes. Additionally, Tasquinimod-d3 acts as an inhibitor of S100A9, highlighting its potential for diverse applications in cancer research and therapeutic development.
Tasquinimod-d3 is a deuterated form of Tasquinimod, an oral antiangiogenic agent targeting castration-resistant prostate cancer. This compound selectively binds to the regulatory Zn2+ binding domain of HDAC4 with a Kd of 10-30 nM, thereby influencing histone deacetylation processes. Additionally, Tasquinimod-d3 acts as an inhibitor of S100A9, highlighting its potential for diverse applications in cancer research and therapeutic development.
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