Taxifolin

Name: Taxifolin
Brand: Adooq Bioscience
SKU: A10893
Rating: 100 (2 reviews)

Catalog No.: A10893

VEGFR-2 Inhibitor

Product Citations (2)

Taxifolin Chemical Structure

CAS NO. 480-18-2

Taxifolin is found to bind at the ATP-binding site on VEGFR-2 kinase with large value of binding energy and act as type I competitive inhibitor.

Availability: In stock

Package	Price	Qty
50 mg	$50.00
100 mg	$80.00
200 mg	$130.00
10mM * 1mL in DMSO	$50.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq Taxifolin

Shinji Kondo, .et al. Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Hyperglycemia and Hyperuricemia, Curr Issues Mol Biol, 2021, Sep 26;43(3):1293-1306 PMID: 34698101
Shin-ichi Adachi, .et al. Anti-hyperuricemic effect of taxifolin in cultured hepatocytes and model mice, Cytotechnology, 2017, Apr; 69(2): 329-336 PMID: 28101741

Biological Activity

Taxifolin is found to bind at the ATP-binding site on VEGFR-2 kinase with large value of binding energy and act as type I competitive inhibitor.

Targets

Solubility *

In vitro	DMSO	56 mg/mL (184.05 mM)
	Water	Insoluble
	Ethanol	56 mg/mL (184.05 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.86 mL	164.31 mL	328.62 mL
0.5 mM	6.57 mL	32.86 mL	65.72 mL
1 mM	3.29 mL	16.43 mL	32.86 mL
5 mM	0.66 mL	3.29 mL	6.57 mL

*The above data is based on the productmolecular weight 304.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A10893
Actions	Inhibitor
CAS No.	480-18-2
Formula	C15H12O7
M. Wt	304.3
Purity	>98%
Synonyms	Dihydroquercetin, Taxifoliol, Distylin, Catechin hydrate, (+)-Taxifolin, trans-Dihydroquercetin, (+)-Dihydroquercetin
SMILES	C1=CC(=C(C=C1[[email protected]@H]2[[email protected]](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.