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Taxifolin is found to bind at the ATP-binding site on VEGFR-2 kinase with large value of binding energy and act as type I competitive inhibitor.
Targets
| In vitro | DMSO | 60 mg/mL (197.2 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 60 mg/mL (197.2 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.86 mL | 164.31 mL | 328.62 mL |
| 0.5 mM | 6.57 mL | 32.86 mL | 65.72 mL |
| 1 mM | 3.29 mL | 16.43 mL | 32.86 mL |
| 5 mM | 0.66 mL | 3.29 mL | 6.57 mL |
*The above data is based on the productmolecular weight 304.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10893 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 304.3 |
| Formula | C15H12O7 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 480-18-2 |
| Synonyms | Dihydroquercetin, Taxifoliol, Distylin, Catechin hydrate, (+)-Taxifolin, trans-Dihydroquercetin, (+)-Dihydroquercetin |
| SMILES | C1=CC(=C(C=C1[[email protected]@H]2[[email protected]](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
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