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TC-E 5002, selective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 uM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.04 mL | 175.2 mL | 350.41 mL |
| 0.5 mM | 7.01 mL | 35.04 mL | 70.08 mL |
| 1 mM | 3.5 mL | 17.52 mL | 35.04 mL |
| 5 mM | 0.7 mL | 3.5 mL | 7.01 mL |
*The above data is based on the productmolecular weight 285.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A16373 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 285.38 |
| Formula | C15H27NO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1453071-47-0 |
| Synonyms | N/A |
| SMILES | O=C(N(O)CCC(O)=O)CCCCCCCCC1CC1 |
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