TCB-32

Catalog No.: A33461
FGFR1 Agonist
TCB-32 is a potent FGFR1 agonist with an EC50 of 0.88 μM, effectively activating the FGFR1 signaling pathway to enhance cell proliferation, notably through the ERK 1/2 cascade. This compound exhibits excellent thermal stability and can serve as a substitute for bFGF in serum-free cell culture environments. TCB-32 is applicable in research related to tissue repair and wound healing, making it suitable for studies investigating conditions such as psoriasis and eczema.
Grouped product items
Size Price Stock Qty
1mg
$335.00
In stock
5mg
$860.00
In stock
10mg
$1,430.00
In stock
25mg
$2,690.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTCB-32 is a potent FGFR1 agonist with an EC50 of 0.88 μM, effectively activating the FGFR1 signaling pathway to enhance cell proliferation, notably through the ERK 1/2 cascade. This compound exhibits excellent thermal stability and can serve as a substitute for bFGF in serum-free cell culture environments. TCB-32 is applicable in research related to tissue repair and wound healing, making it suitable for studies investigating conditions such as psoriasis and eczema.
Product Information
Catalog NumA33461
FormulaC32H40N18O2
Molecular Weight708.78
CAS Number352513-86-1
SMILESC/C(C1=CC(NC(C2=CC(C(NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3)=O)=CC=C2)=O)=CC(/C(C)=N/NC(N)=N)=C1)=N\NC(N)=N
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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