TCS ERK 11e (VX-11e)

Name: TCS ERK 11e (VX-11e)
Brand: Adooq Bioscience
SKU: A12505
Rating: 5 (1 reviews)

Catalog No.: A12505

ERK2 inhibitor

Adooq's TCS ERK 11e (VX-11e) has been cited by 1 publications

TCS ERK 11e (VX-11e) is a potent and selective extracellular signal-related kinase 2 (ERK2) inhibitor (Ki values are <2, 395, 540 and 852 nM for ERK2, GSK-3, Aurora Kinase A and Cdk2 respectively). Potently blocks proliferation of HT29 cells (IC50 = 48 nM).

Skip to the end of the images gallery

TCS ERK 11e (VX-11e) 896720-20-0 ERK2 inhibitor

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
2mg	$45.00	In stock
5mg	$80.00	In stock
10mg	$115.00	In stock
25mg	$215.00	In stock
50mg	$355.00	In stock
100mg	$565.00	In stock
*10mM 1mL in DMSO**	$90.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Research use only. We do not sell to patients.

Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper

Adooq's TCS ERK 11e (VX-11e) has been cited by 1 publications

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Biological Activity

Description

Targets

Target	Value

Product Information

Catalog Num	A12505
Formula	C24H20Cl2FN5O2
Molecular Weight	500.35
CAS Number	896720-20-0
SMILES	CC1=CN=C(N=C1C2=CNC(=C2)C(=O)N[C@H](CO)C3=CC(=CC=C3)Cl)NC4=C(C=C(C=C4)F)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	94 mg/mL (187.87 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (29.97 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.99 mL	99.93 mL	199.86 mL
0.5 mM	4 mL	19.99 mL	39.97 mL
1 mM	2 mL	9.99 mL	19.99 mL
5 mM	0.4 mL	2 mL	4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂