Telapristone acetate

Catalog No.: A32316
Progesterone Receptor Modulator
Telapristone acetate is a potent progesterone receptor modulator that effectively inhibits the proliferation of ovarian cancer cells by inducing cell cycle arrest and apoptosis. This compound has demonstrated efficacy in reducing the incidence and progression of both spontaneous and chemically induced mammary tumors in animal models. Telapristone acetate is valuable for research focused on breast and ovarian cancer, providing insights into its therapeutic potential and mechanisms of action.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTelapristone acetate is a potent progesterone receptor modulator that effectively inhibits the proliferation of ovarian cancer cells by inducing cell cycle arrest and apoptosis. This compound has demonstrated efficacy in reducing the incidence and progression of both spontaneous and chemically induced mammary tumors in animal models. Telapristone acetate is valuable for research focused on breast and ovarian cancer, providing insights into its therapeutic potential and mechanisms of action.
Product Information
Catalog NumA32316
FormulaC31H39NO5
Molecular Weight505.65
CAS Number198414-31-2
SMILESC[C@@]12[C@](CC[C@]2(OC(C)=O)C(COC)=O)([H])[C@@]3([H])C([C@@H](C4=CC=C(N(C)C)C=C4)C1)=C(CC5)C(CC3)=CC5=O
SynonymsCDB-4124
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