Signaling Pathway
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| Discription | Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. | ||
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| Targets |
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| Catalog Num | A10906 |
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| Formula | C56H87NO16 |
| Molecular Weight | 1030.3 |
| CAS Number | 162635-04-3 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C\C=C\[C@H](C[C@H](C(=O)[C@H]([C@H](/C(=C\[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OC(=O)C(C)(CO)CO)C)/C)O)OC)C)C)/C)OC |
| Synonyms | CCI-779 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 60 mg/mL (58.24 mM) | |
| Water | Insoluble | ||
| Ethanol | 67 mg/mL (65.03 mM) | ||
| In vivo | 2% DMSO+30% PEG 300 +2% Tween 80+ddH2O | 6 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.71 mL | 48.53 mL | 97.06 mL |
| 0.5 mM | 1.94 mL | 9.71 mL | 19.41 mL |
| 1 mM | 0.97 mL | 4.85 mL | 9.71 mL |
| 5 mM | 0.19 mL | 0.97 mL | 1.94 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
