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Temsirolimus (Torisel)


mTOR inhibitor

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Catalog No. A10906

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Temsirolimus 10mg A10906-10

Regular Price: €57.00

Special Price: €51.30

Temsirolimus 25mg A10906-25

Regular Price: €133.00

Special Price: €119.70

Temsirolimus 50mg A10906-50

Regular Price: €237.50

Special Price: €213.75

Temsirolimus 200mg A10906-200

Regular Price: €570.00

Special Price: €513.00

Temsirolimus (Torisel) 10mM * 1mL in DMSO A10906-10mM-D

Regular Price: €104.50

Special Price: €94.05

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells.

Temsirolimus (Torisel)

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Chemical Information

Catalog Num A10906
Actions Inhibitor
M. Wt 1030.3
Formula C56H87NO16
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 162635-04-3
Synonyms CCI-779
SMILES C[[email protected]@H]1CC[[email protected]]2C[[email protected]@H](/C(=C/C=C\C=C\[[email protected]](C[[email protected]](C(=O)[[email protected]]([[email protected]](/C(=C\[[email protected]](C(=O)C[[email protected]](OC(=O)[[email protected]@H]3CCCCN3C(=O)C(=O)[[email protected]@]1(O2)O)[[email protected]@H](C)C[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)OC(=O)C(C)(CO)CO)C)/C)O)OC)C)C)/C)OC

Biological Activity

Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells.
mTOR (Cell-free assay)
1.76 μM


Solubility (25°C) * In vitro DMSO 75 mg/mL (72.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 75 mg/mL (72.79 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.71 mL 48.53 mL 97.06mL
0.5 mM 1.94 mL 9.71 mL 19.41 mL
1 mM 0.97 mL 4.85 mL 9.71 mL
5 mM 0.19 mL 0.97 mL 1.94 mL

*The above data is based on the productmolecular weight 1030.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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