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Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.
Targets
| Dipeptidyl peptidase-4 | DPP-9 | DPP-8 | FAP | |
| 1.75 nM | 150 nM | 189 nM | >10 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.95 mL | 39.75 mL | 79.51 mL |
| 0.5 mM | 1.59 mL | 7.95 mL | 15.9 mL |
| 1 mM | 0.8 mL | 3.98 mL | 7.95 mL |
| 5 mM | 0.16 mL | 0.8 mL | 1.59 mL |
*The above data is based on the productmolecular weight 1257.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15258 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 1257.72 |
| Formula | C44H65Br5N12O2S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 906093-29-6 |
| SMILES | CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.Br.Br.Br.Br.Br |
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