Terbequinil

Catalog No.: A66837
GABAA Receptor Inverse Agonist
Terbequinil is a potent inverse agonist of the Gamma-aminobutyric acid A (GABAA) receptor, exhibiting significant oral bioavailability. This compound is valuable for investigations into the modulation of GABAA receptor activity and its implications in various nervous system disorders. Its ability to inhibit receptor signaling makes it a useful tool in exploring therapeutic approaches to conditions influenced by GABAA receptor dysfunction.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTerbequinil is a potent inverse agonist of the Gamma-aminobutyric acid A (GABAA) receptor, exhibiting significant oral bioavailability. This compound is valuable for investigations into the modulation of GABAA receptor activity and its implications in various nervous system disorders. Its ability to inhibit receptor signaling makes it a useful tool in exploring therapeutic approaches to conditions influenced by GABAA receptor dysfunction.
Product Information
Catalog NumA66837
FormulaC15H18N2O3
Molecular Weight274.32
CAS Number113079-82-6
SMILESCOCN1C2=CC=CC=C2C(C(C(NCCC)=O)=C1)=O
SynonymsSR-25776
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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