Terfenadine
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Terfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. | ||
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Catalog Num | A17373 |
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Formula | C32H41NO2 |
Molecular Weight | 471.685 |
CAS Number | 50679-08-8 |
SMILES | OC(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2 |
Synonyms | BRN 5857899; BRN5857899; BRN-5857899; Terfenadine; Seldane; Terfen |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 83 mg/mL (175.97 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 24 mg/mL (50.88 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.2 mL | 106 mL | 212.01 mL |
0.5 mM | 4.24 mL | 21.2 mL | 42.4 mL |
1 mM | 2.12 mL | 10.6 mL | 21.2 mL |
5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2