tert-Butyl (S)-5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate serves as an E3 ligase ligand-linker conjugate specifically designed for the development of PROTACs (proteolysis-targeting chimeras). This compound features a CRBN-based ligand essential for targeted protein degradation mechanisms. Its application in research facilitates the selective modulation of protein levels, contributing to studies in drug discovery and therapeutic development.
tert-Butyl (S)-5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate serves as an E3 ligase ligand-linker conjugate specifically designed for the development of PROTACs (proteolysis-targeting chimeras). This compound features a CRBN-based ligand essential for targeted protein degradation mechanisms. Its application in research facilitates the selective modulation of protein levels, contributing to studies in drug discovery and therapeutic development.
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