Tetrahydroamentoflavone

Catalog No.: A78166
XO Inhibitor
Tetrahydroamentoflavone is a potent xanthine oxidase (XO) inhibitor, demonstrating significant inhibitory activity with IC50 and Ki values of 92 nM and 0.982 μM, respectively. This compound has potential applications in the study of inflammatory disorders and gout, making it a valuable tool for researchers investigating these conditions. Its ability to modulate XO activity positions it as a promising candidate for further exploration in therapeutic contexts.
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Size Price Stock Qty
1mg
$490.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTetrahydroamentoflavone is a potent xanthine oxidase (XO) inhibitor, demonstrating significant inhibitory activity with IC50 and Ki values of 92 nM and 0.982 μM, respectively. This compound has potential applications in the study of inflammatory disorders and gout, making it a valuable tool for researchers investigating these conditions. Its ability to modulate XO activity positions it as a promising candidate for further exploration in therapeutic contexts.
Product Information
Catalog NumA78166
FormulaC30H22O10
Molecular Weight542.49
CAS Number48236-96-0
SMILESOC1=CC(O)=C(C(C[C@@H](C2=CC=C(C=C2)O)O3)=O)C3=C1C4=CC([C@H]5OC6=CC(O)=CC(O)=C6C(C5)=O)=CC=C4O
SynonymsAmentoflavanone
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