Tetrahydromagnolol, a potent and selective agonist of the cannabinoid CB2 receptor, exhibits an EC50 value of 170 nM. It has a binding affinity (Ki) for the CB2 receptor of 416 nM, which is significantly higher compared to the CB1 receptor. This compound demonstrates notable biological activities, including antifungal, anti-inflammatory, and analgesic effects, making it valuable for research in pain management and inflammatory disorders. Additionally, its role as a GPR55 antagonist further enhances its potential utility in cannabinoid-related studies.
Tetrahydromagnolol, a potent and selective agonist of the cannabinoid CB2 receptor, exhibits an EC50 value of 170 nM. It has a binding affinity (Ki) for the CB2 receptor of 416 nM, which is significantly higher compared to the CB1 receptor. This compound demonstrates notable biological activities, including antifungal, anti-inflammatory, and analgesic effects, making it valuable for research in pain management and inflammatory disorders. Additionally, its role as a GPR55 antagonist further enhances its potential utility in cannabinoid-related studies.
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