Thalidomide-(1-(3-azetidinylmethyl)piperazine) is an E3 ligase ligand-linker conjugate designed for targeted protein degradation via the PROTAC (proteolysis-targeting chimera) platform. This compound features a CRBN-based ligand that facilitates the recruitment of E3 ubiquitin ligase, enabling selective degradation of target proteins. It is a valuable tool for researchers investigating protein regulation, cellular pathways, and therapeutic strategies in drug discovery and development.
Thalidomide-(1-(3-azetidinylmethyl)piperazine) is an E3 ligase ligand-linker conjugate designed for targeted protein degradation via the PROTAC (proteolysis-targeting chimera) platform. This compound features a CRBN-based ligand that facilitates the recruitment of E3 ubiquitin ligase, enabling selective degradation of target proteins. It is a valuable tool for researchers investigating protein regulation, cellular pathways, and therapeutic strategies in drug discovery and development.
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