Thalidomide-4-O-C4-Br is an E3 ligase ligand-linker conjugate derived from thalidomide, specifically targeting the cereblon (CRBN) E3 ubiquitin ligase. This compound facilitates the formation of PROTACs, enabling targeted protein degradation, with applications in cancer research and therapeutic development. Thalidomide-4-O-C4-Br can be utilized to generate conjugates such as PROTAC EZH2 Degrader-10, which are designed to selectively degrade specific proteins of interest in a cellular context.
Thalidomide-4-O-C4-Br is an E3 ligase ligand-linker conjugate derived from thalidomide, specifically targeting the cereblon (CRBN) E3 ubiquitin ligase. This compound facilitates the formation of PROTACs, enabling targeted protein degradation, with applications in cancer research and therapeutic development. Thalidomide-4-O-C4-Br can be utilized to generate conjugates such as PROTAC EZH2 Degrader-10, which are designed to selectively degrade specific proteins of interest in a cellular context.
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