Thalidomide-4-O-C5-Br is a synthetic E3 ligase ligand-linker conjugate that features a thalidomide-derived CRBN ligand combined with a versatile linker suitable for PROTAC applications. This compound facilitates the targeted degradation of specific proteins, exemplified by its role in the formation of PROTAC EZH2 Degrader-11. Thalidomide-4-O-C5-Br serves as a valuable tool for researchers investigating targeted protein degradation and the modulation of cellular pathways.
Thalidomide-4-O-C5-Br is a synthetic E3 ligase ligand-linker conjugate that features a thalidomide-derived CRBN ligand combined with a versatile linker suitable for PROTAC applications. This compound facilitates the targeted degradation of specific proteins, exemplified by its role in the formation of PROTAC EZH2 Degrader-11. Thalidomide-4-O-C5-Br serves as a valuable tool for researchers investigating targeted protein degradation and the modulation of cellular pathways.
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