Thalidomide-4-O-C8-Br is an E3 ligase ligand-linker conjugate that integrates the Thalidomide-derived CRBN ligand with a linear linker designed for PROTAC applications. This reagent facilitates the targeted degradation of proteins, exemplified by its use in the synthesis of PROTAC EZH2 Degrader-15. Thalidomide-4-O-C8-Br is an essential tool for researchers exploring protein regulation and degradation pathways in cellular processes.
Thalidomide-4-O-C8-Br is an E3 ligase ligand-linker conjugate that integrates the Thalidomide-derived CRBN ligand with a linear linker designed for PROTAC applications. This reagent facilitates the targeted degradation of proteins, exemplified by its use in the synthesis of PROTAC EZH2 Degrader-15. Thalidomide-4-O-C8-Br is an essential tool for researchers exploring protein regulation and degradation pathways in cellular processes.
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