Thalidomide-4-O-C8-NH2 is an E3 ligase ligand-linker conjugate integrating a Thalidomide-derived cereblon ligand with a C8 linker, designed for use in PROTAC (proteolysis-targeting chimera) applications. This compound facilitates targeted protein degradation by harnessing the ubiquitin-proteasome system, thereby enabling the selective modulation of protein levels within cellular environments. Its primary applications lie in the development of novel therapeutics and research in cellular pathways regulated by ubiquitination.
Thalidomide-4-O-C8-NH2 is an E3 ligase ligand-linker conjugate integrating a Thalidomide-derived cereblon ligand with a C8 linker, designed for use in PROTAC (proteolysis-targeting chimera) applications. This compound facilitates targeted protein degradation by harnessing the ubiquitin-proteasome system, thereby enabling the selective modulation of protein levels within cellular environments. Its primary applications lie in the development of novel therapeutics and research in cellular pathways regulated by ubiquitination.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
