Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound serves as a key building block for the synthesis of PROTAC GSPT1 degrader-1, enabling selective degradation of the target protein. It is useful in studies aimed at elucidating protein function and developing novel therapeutic strategies through targeted ubiquitination pathways.
Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound serves as a key building block for the synthesis of PROTAC GSPT1 degrader-1, enabling selective degradation of the target protein. It is useful in studies aimed at elucidating protein function and developing novel therapeutic strategies through targeted ubiquitination pathways.
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