Thalidomide 5-fluoride 6-piperidine-C-OH is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN)-based ligand with a functional linker. This compound is utilized in the synthesis of PROTACs, enabling targeted protein degradation through the modulation of E3 ligase activity. Its unique structure facilitates the development of novel therapeutic agents in cellular and molecular biology research.
Thalidomide 5-fluoride 6-piperidine-C-OH is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN)-based ligand with a functional linker. This compound is utilized in the synthesis of PROTACs, enabling targeted protein degradation through the modulation of E3 ligase activity. Its unique structure facilitates the development of novel therapeutic agents in cellular and molecular biology research.
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