Thalidomide-5-PEG3-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a polyethylene glycol (PEG) linker. This compound facilitates the recruitment of target proteins to the E3 ligase, enhancing targeted protein degradation via PROTAC (Proteolysis Targeting Chimera) technology. It serves as a valuable tool for research in protein modulation, cellular signaling pathways, and therapeutic development in oncology and other diseases.
Thalidomide-5-PEG3-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a polyethylene glycol (PEG) linker. This compound facilitates the recruitment of target proteins to the E3 ligase, enhancing targeted protein degradation via PROTAC (Proteolysis Targeting Chimera) technology. It serves as a valuable tool for research in protein modulation, cellular signaling pathways, and therapeutic development in oncology and other diseases.
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