Thalidomide-azetidine-C-OH is an E3 ligase ligand-linker conjugate that features a CRBN-based ligand combined with a linker moiety. This compound facilitates the design and synthesis of PROTACs, which are innovative bifunctional molecules capable of targeting and ubiquitinating specific proteins for degradation. With its potential applications in targeted protein degradation studies, Thalidomide-azetidine-C-OH serves as a valuable tool for researchers investigating cellular signaling pathways and protein homeostasis.
Thalidomide-azetidine-C-OH is an E3 ligase ligand-linker conjugate that features a CRBN-based ligand combined with a linker moiety. This compound facilitates the design and synthesis of PROTACs, which are innovative bifunctional molecules capable of targeting and ubiquitinating specific proteins for degradation. With its potential applications in targeted protein degradation studies, Thalidomide-azetidine-C-OH serves as a valuable tool for researchers investigating cellular signaling pathways and protein homeostasis.
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