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Thalidomide-azetidine-CHO

E3 Ligase Ligand-Linker Conjugates

Thalidomide-azetidine-CHO is a synthesized ligand designed for E3 ligase applications, incorporating the thalidomide-based cereblon ligand. This compound enables targeted protein degradation through the PROTAC technology, facilitating precise modulation of protein levels within cells. Its key biological activity and role as a linker conjugate make it suitable for diverse research applications in drug discovery and cellular biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2416132-70-0
Applications	E3 Ligase Ligand-Linker Conjugates
Formula	C₁₇H₁₅N₃O₅
Molecular Weight	341.32
SMILES	O=C1N(C2CCC(NC2=O)=O)C(C3=CC=C(N4CC(C=O)C4)C=C31)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.