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Thalidomide fluoride

Catalog No.: A12144
Thalidomide-based Cereblon ligand

Thalidomide fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Thalidomide fluoride
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Product Name Price Stock Qty
Thalidomide fluoride 50mg
$63.00
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Thalidomide fluoride 100mg
$109.00
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Thalidomide fluoride 500mg
$322.00
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Biological Activity
Discription

Thalidomide fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
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Product Information
Catalog Num A12144
Formula C13H9FN2O4
Molecular Weight 276.22
CAS Number 835616-60-9
SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O
Synonyms Cereblon ligand 4; E3 ligase Ligand 4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTACs > E3 Ligase Ligands
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