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Thalidomide-NH-C10-COOH

Catalog No.: A30880
E3 Ligase Ligand-Linker Conjugates
Thalidomide-NH-C10-COOH is an E3 ligase ligand-linker conjugate that features a Thalidomide-derived CRBN ligand. This compound is designed for use in PROTAC (proteolysis-targeting chimera) technology, enabling selective degradation of target proteins. Its biological activity is critical for research applications focused on targeted protein degradation and cellular modulation in various therapeutic contexts.
Thalidomide-NH-C10-COOH 2428400-33-1 E3 Ligase Ligand-Linker Conjugates
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Size Price Stock Qty
100mg
$830.00
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250mg
$1,270.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-C10-COOH is an E3 ligase ligand-linker conjugate that features a Thalidomide-derived CRBN ligand. This compound is designed for use in PROTAC (proteolysis-targeting chimera) technology, enabling selective degradation of target proteins. Its biological activity is critical for research applications focused on targeted protein degradation and cellular modulation in various therapeutic contexts.
Product Information
Catalog NumA30880
FormulaC24H31N3O6
Molecular Weight457.52
CAS Number2428400-33-1
SMILESO=C(N(C1=O)C(C(N2)=O)CCC2=O)C3=C1C=CC=C3NCCCCCCCCCCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > E3 Ligase Ligand-Linker Conjugate