Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate that features a Thalidomide-derived cereblon ligand paired with a polyethylene glycol (PEG) linker. This compound is designed for use in PROTAC (Proteolysis Targeting Chimeric) strategies, specifically for the degradation of BCL-XL through targeted ubiquitination. Its capabilities enable precise modulation of protein levels, facilitating research in targeted protein degradation and its applications in cancer therapy.
Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate that features a Thalidomide-derived cereblon ligand paired with a polyethylene glycol (PEG) linker. This compound is designed for use in PROTAC (Proteolysis Targeting Chimeric) strategies, specifically for the degradation of BCL-XL through targeted ubiquitination. Its capabilities enable precise modulation of protein levels, facilitating research in targeted protein degradation and its applications in cancer therapy.
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