Thalidomide-NH-C5-NH2 hydrochloride

Catalog No.: A30867
E3 Ligase Ligand-Linker Conjugates
Thalidomide-NH-C5-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines a Thalidomide-derived cereblon ligand with a specialized linker utilized in PROTAC technology. This compound facilitates selective protein degradation by engaging the E3 ubiquitin ligase pathway, making it a valuable tool for investigating targeted protein modulation and therapeutic applications in cancer research and other diseases. Its structural design enhances its potential in developing targeted protein degradation strategies.
Grouped product items
Size Price Stock Qty
5mg
$25.00
In stock
25mg
$30.00
In stock
50mg
$40.00
In stock
100mg
$65.00
In stock
250mg
$140.00
In stock
1g
$565.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-C5-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that combines a Thalidomide-derived cereblon ligand with a specialized linker utilized in PROTAC technology. This compound facilitates selective protein degradation by engaging the E3 ubiquitin ligase pathway, making it a valuable tool for investigating targeted protein modulation and therapeutic applications in cancer research and other diseases. Its structural design enhances its potential in developing targeted protein degradation strategies.
Product Information
Catalog NumA30867
FormulaC18H23ClN4O4
Molecular Weight394.85
CAS Number2375194-03-7
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCN)=O.[H]Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2