Thalidomide-NH-C6-NH2 TFA

Catalog No.: A31208
E3 Ligase Ligand-Linker Conjugate
Thalidomide-NH-C6-NH2 TFA is an E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from thalidomide with a hexylamine linker. This compound is designed for use in PROTAC technology, facilitating targeted protein degradation. It demonstrates significant potential in biochemical research, particularly in drug discovery and development focused on modulating protein levels through E3 ligase recruitment.
Grouped product items
Size Price Stock Qty
2mg
$50.00
In stock
5mg
$80.00
In stock
50mg
$280.00
In stock
100mg
$440.00
In stock
250mg
$765.00
In stock
500mg
$1,055.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-C6-NH2 TFA is an E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from thalidomide with a hexylamine linker. This compound is designed for use in PROTAC technology, facilitating targeted protein degradation. It demonstrates significant potential in biochemical research, particularly in drug discovery and development focused on modulating protein levels through E3 ligase recruitment.
Product Information
Catalog NumA31208
FormulaC21H25F3N4O6
Molecular Weight486.44
CAS Number2093386-51-5
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCN)=O.OC(C(F)(F)F)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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