Thalidomide-NH-PEG2-C2-NH-Boc is an E3 ligase ligand-linker conjugate that features a thalidomide-based cereblon ligand combined with a polyethylene glycol (PEG) linker. This compound is designed for the synthesis of dBRD9, a selective PROTAC degrader that targets BRD9, facilitating investigations into BAF complex biology. It serves as a valuable tool in research applications focused on targeted protein degradation and the modulation of cellular pathways.
Thalidomide-NH-PEG2-C2-NH-Boc is an E3 ligase ligand-linker conjugate that features a thalidomide-based cereblon ligand combined with a polyethylene glycol (PEG) linker. This compound is designed for the synthesis of dBRD9, a selective PROTAC degrader that targets BRD9, facilitating investigations into BAF complex biology. It serves as a valuable tool in research applications focused on targeted protein degradation and the modulation of cellular pathways.
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