Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate designed to facilitate the synthesis of dCBP-1. This compound acts as a potent and selective heterobifunctional degrader targeting the p300/CBP proteins, enabling targeted protein degradation for research applications in cellular processes, epigenetics, and cancer biology. Researchers can utilize this conjugate to explore pathways and mechanisms regulated by p300/CBP, advancing the understanding of transcriptional regulation and related therapeutic strategies.
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate designed to facilitate the synthesis of dCBP-1. This compound acts as a potent and selective heterobifunctional degrader targeting the p300/CBP proteins, enabling targeted protein degradation for research applications in cellular processes, epigenetics, and cancer biology. Researchers can utilize this conjugate to explore pathways and mechanisms regulated by p300/CBP, advancing the understanding of transcriptional regulation and related therapeutic strategies.
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