Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound facilitates the formation of PROTAC iRucaparib-AP6, a highly specific degrader of PARP1, by linking to the target protein via a linker. Its primary mechanism involves enhancing protein degradation pathways, offering significant potential in targeted protein knockdown studies and cancer research.
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound facilitates the formation of PROTAC iRucaparib-AP6, a highly specific degrader of PARP1, by linking to the target protein via a linker. Its primary mechanism involves enhancing protein degradation pathways, offering significant potential in targeted protein knockdown studies and cancer research.
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