Thalidomide-O-amide-C5-NH2 TFA is an E3 ligase ligand-linker conjugate that contains the thalidomide-derived cereblon ligand and a C5 amino linker, facilitating targeted protein degradation via PROTAC technology. This reagent is designed for research applications involving the modulation of protein homeostasis and the therapeutic potential of targeted protein degradation strategies. Its unique structure enables the selective recruitment of E3 ligases, thus enhancing the efficacy of drug discovery and development processes involving the ubiquitin-proteasome system.
Thalidomide-O-amide-C5-NH2 TFA is an E3 ligase ligand-linker conjugate that contains the thalidomide-derived cereblon ligand and a C5 amino linker, facilitating targeted protein degradation via PROTAC technology. This reagent is designed for research applications involving the modulation of protein homeostasis and the therapeutic potential of targeted protein degradation strategies. Its unique structure enables the selective recruitment of E3 ligases, thus enhancing the efficacy of drug discovery and development processes involving the ubiquitin-proteasome system.
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