Thalidomide-O-amido-C11-COOH

Name: Thalidomide-O-amido-C11-COOH
Brand: Adooq Bioscience
SKU: A80270
Rating: 5 (288 reviews)

Catalog No.: A80270

E3 Ligase Ligand- Linker Conjugate

Thalidomide-O-amido-C11-COOH is an E3 ligase ligand and a linker conjugate for CRBN (Cereblon). This compound facilitates the synthesis of PROTACs designed to promote the degradation of DOT1L. Its unique structure allows for targeted protein degradation, making it a valuable tool for research in cellular regulation and therapeutic development.

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Thalidomide-O-amido-C11-COOH 2473270-96-9 E3 Ligase Ligand- Linker Conjugate

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Biological Activity

Description	Thalidomide-O-amido-C11-COOH is an E3 ligase ligand and a linker conjugate for CRBN (Cereblon). This compound facilitates the synthesis of PROTACs designed to promote the degradation of DOT1L. Its unique structure allows for targeted protein degradation, making it a valuable tool for research in cellular regulation and therapeutic development.

Product Information

Catalog Num	A80270
Formula	C27H35N3O8
Molecular Weight	529.58
CAS Number	2473270-96-9
SMILES	O=C(CCCCCCCCCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)O

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