Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand derived from Thalidomide. This compound is designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation in cellular systems. Its unique structure allows for selective engagement of E3 ligases, providing valuable applications in therapeutic research and drug discovery focused on the modulation of protein levels.
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand derived from Thalidomide. This compound is designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation in cellular systems. Its unique structure allows for selective engagement of E3 ligases, providing valuable applications in therapeutic research and drug discovery focused on the modulation of protein levels.
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