Thalidomide-O-amido-PEG-C2-NH2 is an E3 ligase ligand-linker conjugate designed to target cereblon, a substrate recognition component of the ubiquitin-proteasome system. This compound facilitates protein degradation via PROTAC technology, enabling the selective modulation of protein levels within cells. Its application is particularly relevant in studies of gene regulation and targeted therapy development in various diseases, including cancer.
Thalidomide-O-amido-PEG-C2-NH2 is an E3 ligase ligand-linker conjugate designed to target cereblon, a substrate recognition component of the ubiquitin-proteasome system. This compound facilitates protein degradation via PROTAC technology, enabling the selective modulation of protein levels within cells. Its application is particularly relevant in studies of gene regulation and targeted therapy development in various diseases, including cancer.
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