Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

Catalog No.: A21634

E3 ligase ligand-linker conjugate

Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

Thalidomide-O-amido-PEG2-C2-NH2 (TFA) Chemical Structure

CAS NO. 1957235-75-4

Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

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500 mg
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Biological Activity

Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.35 mL 86.73 mL 173.47 mL
0.5 mM 3.47 mL 17.35 mL 34.69 mL
1 mM 1.73 mL 8.67 mL 17.35 mL
5 mM 0.35 mL 1.73 mL 3.47 mL

*The above data is based on the productmolecular weight 576.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21634
M. Wt 576.48
Formula C23H27F3N4O10
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1957235-75-4
Synonyms Cereblon Ligand-Linker Conjugates 10 (TFA); E3 Ligase Ligand-Linker Conjugates 24 (TFA)
SMILES O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F

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