Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride serves as a synthesized E3 ligase ligand-linker conjugate, featuring a cereblon ligand derived from Thalidomide and a three-unit polyethylene glycol (PEG) linker. This compound is essential for the development of proteolysis-targeting chimeras (PROTACs), enabling targeted degradation of specific proteins in cellular research. Its unique structure facilitates effective interactions with E3 ligases, making it a valuable tool for studying protein regulation and potential therapeutic applications in cancer and other diseases.
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride serves as a synthesized E3 ligase ligand-linker conjugate, featuring a cereblon ligand derived from Thalidomide and a three-unit polyethylene glycol (PEG) linker. This compound is essential for the development of proteolysis-targeting chimeras (PROTACs), enabling targeted degradation of specific proteins in cellular research. Its unique structure facilitates effective interactions with E3 ligases, making it a valuable tool for studying protein regulation and potential therapeutic applications in cancer and other diseases.
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