Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a substrate receptor in the CRL4 ubiquitin-proteasome system. This compound facilitates the development of proteolysis-targeting chimeras (PROTACs), offering a novel approach for selective protein degradation in various biological research applications. Its unique structure allows for the effective modulation of protein levels, making it a valuable tool in cellular biology and therapeutic research.
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a substrate receptor in the CRL4 ubiquitin-proteasome system. This compound facilitates the development of proteolysis-targeting chimeras (PROTACs), offering a novel approach for selective protein degradation in various biological research applications. Its unique structure allows for the effective modulation of protein levels, making it a valuable tool in cellular biology and therapeutic research.
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