Thalidomide-O-C11-acid is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a substrate receptor for E3 ligases. This compound is designed for use in PROTAC (proteolysis-targeting chimera) technology and facilitates the targeted degradation of proteins through the ubiquitin-proteasome system. It serves as a valuable tool for research into proteostasis and potential therapeutic interventions.
Thalidomide-O-C11-acid is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a substrate receptor for E3 ligases. This compound is designed for use in PROTAC (proteolysis-targeting chimera) technology and facilitates the targeted degradation of proteins through the ubiquitin-proteasome system. It serves as a valuable tool for research into proteostasis and potential therapeutic interventions.
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