Thalidomide-O-C2-acid is an E3 ligase ligand-linker conjugate that features the Thalidomide-derived cereblon ligand, combined with a suitable linker for applications in PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates targeted protein degradation, enabling researchers to manipulate protein levels within cells. Its design supports the development of innovative therapeutic strategies by leveraging the ubiquitin-proteasome system for potential applications in cancer and other diseases.
Thalidomide-O-C2-acid is an E3 ligase ligand-linker conjugate that features the Thalidomide-derived cereblon ligand, combined with a suitable linker for applications in PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates targeted protein degradation, enabling researchers to manipulate protein levels within cells. Its design supports the development of innovative therapeutic strategies by leveraging the ubiquitin-proteasome system for potential applications in cancer and other diseases.
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