Thalidomide-OCH2-amide-PEG2-C2-Boc is a ligand-linker conjugate designed for E3 ligase targeting, specifically interacting with the cereblon (CRBN) E3 ubiquitin ligase. This compound facilitates the development of PROTACs, including SARS-CoV-2 Degrader-1, making it valuable for research in targeted protein degradation and therapeutic applications against viral infections. Its structural components ensure efficient conjugation for effective modulation of protein levels within cellular systems.
Thalidomide-OCH2-amide-PEG2-C2-Boc is a ligand-linker conjugate designed for E3 ligase targeting, specifically interacting with the cereblon (CRBN) E3 ubiquitin ligase. This compound facilitates the development of PROTACs, including SARS-CoV-2 Degrader-1, making it valuable for research in targeted protein degradation and therapeutic applications against viral infections. Its structural components ensure efficient conjugation for effective modulation of protein levels within cellular systems.
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