Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate designed to target the cereblon E3 ligase. This compound utilizes a PEG-based linker, enabling its application in PROTAC (Proteolysis Targeting Chimera) technology for targeted protein degradation. Thalidomide-PEG2-NH2 facilitates the selective modulation of protein levels, providing a valuable tool for research in cellular signaling, cancer biology, and pharmacological studies.
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate designed to target the cereblon E3 ligase. This compound utilizes a PEG-based linker, enabling its application in PROTAC (Proteolysis Targeting Chimera) technology for targeted protein degradation. Thalidomide-PEG2-NH2 facilitates the selective modulation of protein levels, providing a valuable tool for research in cellular signaling, cancer biology, and pharmacological studies.
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