Thalidomide-PEG4-Propargyl is an E3 ligase ligand-linker conjugate that features the cereblon ligand derived from Thalidomide, along with a PEG4 linker designed for PROTAC technology. This compound serves as a versatile click chemistry reagent due to its alkyne functionality, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties facilitate targeted protein degradation and make it valuable for research applications in drug discovery and protein modulation.
Thalidomide-PEG4-Propargyl is an E3 ligase ligand-linker conjugate that features the cereblon ligand derived from Thalidomide, along with a PEG4 linker designed for PROTAC technology. This compound serves as a versatile click chemistry reagent due to its alkyne functionality, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties facilitate targeted protein degradation and make it valuable for research applications in drug discovery and protein modulation.
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