Thalidomide-Pip-4-one is an E3 ligase ligand-linker conjugate that consists of a CRBN-based ligand and an optimized linker. This compound is utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs), which enable targeted protein degradation. Its applications in chemical biology facilitate the study of protein dynamics and the modulation of biological pathways in various research settings.
Thalidomide-Pip-4-one is an E3 ligase ligand-linker conjugate that consists of a CRBN-based ligand and an optimized linker. This compound is utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs), which enable targeted protein degradation. Its applications in chemical biology facilitate the study of protein dynamics and the modulation of biological pathways in various research settings.
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