Thalidomide-Piperazine 5-fluoride

Catalog No.: A30778
E3 Ligase Ligand-Linker Conjugates
Thalidomide-Piperazine 5-fluoride is a synthesized compound that functions as an E3 ligase ligand-linker conjugate, featuring the Thalidomide-derived cereblon ligand. This reagent is designed for applications in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating targeted protein degradation. Its unique structure allows for effective modulation of protein levels in experimental settings, making it a valuable tool in the study of cellular processes and therapeutic development.
Grouped product items
Size Price Stock Qty
100mg
$70.00
In stock
250mg
$90.00
In stock
1g
$225.00
In stock
5g
$675.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-Piperazine 5-fluoride is a synthesized compound that functions as an E3 ligase ligand-linker conjugate, featuring the Thalidomide-derived cereblon ligand. This reagent is designed for applications in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating targeted protein degradation. Its unique structure allows for effective modulation of protein levels in experimental settings, making it a valuable tool in the study of cellular processes and therapeutic development.
Product Information
Catalog NumA30778
FormulaC17H17FN4O4
Molecular Weight360.34
CAS Number2222114-22-7
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(N4CCNCC4)C(F)=C3)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2