Thalidomide-piperidin-C-piperidin

Catalog No.: A80411
E3 Ligase Ligand-Linker Conjugate
Thalidomide-piperidin-C-piperidin is an E3 ligase ligand-linker conjugate that includes a CRBN-based ligand. This compound is designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras), enabling targeted protein degradation. It serves as a versatile tool in drug discovery and basic research aimed at modulating protein levels within biological systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-piperidin-C-piperidin is an E3 ligase ligand-linker conjugate that includes a CRBN-based ligand. This compound is designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras), enabling targeted protein degradation. It serves as a versatile tool in drug discovery and basic research aimed at modulating protein levels within biological systems.
Product Information
Catalog NumA80411
FormulaC24H30N4O4
Molecular Weight438.53
CAS Number2714477-27-5
SMILESO=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)N4CCC(CC4)CC5CCNCC5)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2